He traded on various items ranging from palm produce, fabrics (Georges), Potash, guns, and gunpowder, alcoholic beverages (wines and spirits) and ornamental accessories, such as coral beads, elephant tusks and jewelry. His trading activities took him to various parts of Eastern Nigeria. Nze Anyiam married a total of 25 wives but Lolo Nworie was the fourth in order of seniority. She was of good birth but her parents were by no means rich when compared to the affluence, power and means associated with her husband’s antecedents. However, Nworie was a strong willed, energetic and industrious woman who was all embracing in her perspective and conduct in the Large and complex domain of Nze Anyiam. Lolo Nworie was to become a renowned and successful trader, nick named “Aka Na Eme Ego ” (the hand that generates money). Like the men folk did to her husband, other women looked up to her for Leadership.

Onyechere lost his mother when he was three years old and his father died when he was nine. His older brother, Barrister Uriah U. Anyiam-Osigwe, put him through school. He attended elementary school in Okigwe and went to Government College Umuahia. He however completed his secondary education at Dennis Memorial Grammar School, Onitsha owning to the closure of Government College Umuahia at the onset of the second world war.

He started his working life as a post and telegraph clerk. He resigned after two years to go into business. He discovered the highly curative elixir called Obetau, which was marketed throughout the country particularly the Northern and Eastern regions. He was admitted to study Medicine at the South West College kansas state University in the USA. However, he opted to study philosophy and Business through distance learning and private lectures. He established a correspondence school of Esoteric Studies, The West African Academy of Sciences (Truth Seekers), which was dedicated to the study of Man as a Manifestation of Divine Intelligence. He toured various parts of northern Nigeria lecturing and delivering seminars on moral conduct and spirituality.

His energy and entrepreneurial skills enabled him engage in various endeavors, his interests spanning a broad spectrum of Commerce and Industry such as trading, farming, shipping, mining, petroleum, fiduciary institutions and information Technology. He is acknowledged as being instrumental to the increase in revenue accruing to Nigeria from the sale of High Pour Fuel Oil between 1973 and 1979. He also contributed to bringing about the participation of Nigerians in the Petroleum Sector as Independent Marketers. His concern for the disadvantage in the society at Large and the realization that some problems are best solved by government, led him to embrace partisan politics.

He was one of the founding fathers of the Nigeria National Congress (NNC), one of the 13 political associations that were denied registration under the Babangida Transition programme. He ultimately joined the SDP where his brand of “Clean politics” earned him the description “Missionary politician”. He contested for the Governorship of Imo State in 1992. This exercise sharpened his understanding of the National problems. Though his Gubernatorial bid was unsuccessful, he sought to build positively on that experience.